Description
Ship's engineer Andrew Braddock (Michael York) and two other men are floating in a lifeboat in the middle of the Pacific Ocean following the wreck of the ship Lady Vain. One dies at sea. After seventeen days at sea, Braddock and the other man land on an island, where the other man accompanying Braddock is promptly killed by animals. Braddock is nursed back to health in the compound governed by the mysterious scientist "Dr. Moreau" (Burt Lancaster). Besides Moreau, the inhabitants of the compound include Moreau's associate, Montgomery (Nigel Davenport), a mercenary; Moreau's mute, misshapen servant, M'Ling (Nick Cravat); and a ravishing young woman named Maria (Barbara Carrera). Moreau warns Braddock not to leave the compound at night.
Moreau welcomes Braddock as an honored guest and willingly shares his fine library, but there are some strange goings-on. One day, Braddock witnesses Moreau and Montgomery manhandling a chained creature who is clearly not quite human, and the island is home to more than just this one. The Sayer of the Law (Richard Basehart) recites the laws Moreau passed on to them. Moreau explains that they are, in fact, the hybrid products of his experiments upon various species of wild animal. Braddock is both shocked and curious. Moreau explains that he is injecting the animals with a serum containing human genetic material. At times, the human/animal hybrids still have their animal instincts and do not quite behave like a human. This sometimes enrages Moreau, who is left feeling that his experiments have not worked successfully. That night as Braddock is reeling from learning the truth, Maria goes to his room where they have sex. It is implied that this is intended by Moreau.
The following day, Braddock takes a rifle and leaves the compound, determined to see exactly how the hybrid creatures live. He enters a cave and finds several of them (all male). Just as he is surrounded by them and about to use the rifle to defend himself, Moreau appears and restores order. The Sayer of the Law is the only one of Moreau's experimental beasts who can speak. Moreau calls on him to utter the three laws (no going around on all fours, no eating of human flesh, and no taking of other life) aloud to the other creatures. This reminds them that they must not attack Braddock.
After the Bull-Man (Bob Ozman) kills a tiger, Moreau intends to take it to the "house of pain," his laboratory, as punishment. The Bull-Man panics and runs. Braddock finds it in the jungle, badly injured, where it begs him to kill it rather than return it to the lab. Braddock shoots it. This has the effect of angering the man-beasts as Braddock has broken the law of killing.
Convinced that Moreau is insane, Braddock prepares to leave the island with Maria. Moreau stops them and straps Braddock to the table in his lab. He then injects him with another serum so that he can hear Braddock describe the experience of becoming animalistic. Caged, Braddock struggles to maintain his humanity. When Montgomery objects to this treatment and threatens Moreau's life, Moreau shoots him.
Outside the compound, the angry man-beasts turn on Moreau because by killing Montgomery, he has broken the very law he expected them to follow. Moreau is mortally wounded at the compound's gate while trying to whip his attackers into submission. The man-beasts, now overpowered by their primitive instincts, go on a rampage to try and break into the compound and destroy the house of pain as the Sayer of the Law states "There is no law."[a]
Braddock (still struggling to remain human), Maria, M'Ling, and the still-coherent and benign beastfolk servant women stave them off. Braddock resists killing Moreau, who dies of his injuries. Braddock uses the corpse as a diversion so they can escape through the compound. Eventually, the man-beasts break in and the compound is burned. In the chaos, the wild animals which Moreau kept for his experiments are turned loose and a battle ensues between them and the hybrids. Most of the man-beasts are killed by the animals or consumed by the fire, the Sayer of the Law's throat torn out by a tiger, the Bear-Man tackled off a roof by a black panther, and the Lion-Man is mauled by a normal lion. During the final escape, M'Ling risks his life to save his companions from a lion and both fall into a pit trap.
Braddock and Maria manage to float away in the lifeboat that Braddock arrived in, but are followed by the Hyena-Man (Fumio Demura) who is one of the last man-beasts. After a battle with each other, Braddock kills the Hyena-Man with a broken oar. Sometime later, they see a passing ship, and the serum has worn off, returning Braddock to his full human state as Maria looks on with cat-themed eyes.